About

After a PhD in Computer Science, I went back to medical school to get a M.D. Now, I specialize in molecular genetics. I also contribute frequently to open-source projects, especially for Nix packages in bioinformatics.

Research

Publications:

Dellal, Hadjer, Roman Klifa, Lise Larcher, et al. 2026. “From a Novel Pathogenic SAMD9L Variant to Cohort‐wide Insights: Whole‐genome Sequencing Highlights Somatic Genetic Rescue and Phenotypic Heterogeneity.” British Journal of Haematology, ahead of print, May.
Labalette, Vincent, Alexis Praga, Florent Girard, Martine Meireles, Yannick Hallez, and Jeffrey F. Morris. 2021. “Shear-Induced Glass-to-Crystal Transition in Anisotropic Clay-Like Suspensions.” Soft Matter 17 (11): 3174–90.
Praga, A., D. Cariolle, and L. Giraud. 2015. “Pangolin V1.0, a Conservative 2-d Advection Model Towards Large-Scale Parallel Calculation.” Geoscientific Model Development 8 (2): 205–20.
Praga, A., T. Z. Hirsch, D. Vidaud, et al. 2025. “Hepatoblastoma in a Patient with Neurofibromatosis Type 1: A Case Report.” Cancer Genetics
Dellal H, Klifa R, Larcher L, Passet M, Celse T, Gouas L, Tusseau M; AURAGEN Consortium; Praga A, Bernard V, Fusaro M. From a novel pathogenic SAMD9L variant to cohort-wide insights: Whole-genome sequencing highlights somatic genetic rescue and phenotypic heterogeneity. Br J Haematol. 2026 May 19. doi: 10.1111/bjh.70563. Epub ahead of print. PMID: 42154215.

Talks:

Assises de Génétique (2026): BARACUDA : Un outil de priorisation et visualisation des aneuploïdies et des disomies uniparentales en mosaïque dans les maladies rares
ACLF (2025) : BARACUDA : Un outil de priorisation et visualisation des CNV en mosaïques et des disomies uniparentales dans les maladies rares
FOSDEM (2024) : Nix for genetics : powering a bioinformatics pipeline (lighthing talk) - slides, official website
JCADD (2024) : Un pipeline reproductible pour la réanalyse de données d'exome en génétique - slides, talk, source code (Software Heritage)

Others:

PhD manuscript: A large-scale atmospheric chemistry-transport model for massively parallel architectures
Medical thesis: Un pipeline bioinformatique de ré-interprétation d'analyses constitutionnelles d'exome

Open-Source

With my fellow co-organizers, we added Bioinformatics at FOSDEM:

2024: my talk about Nix (see above)
2025 : Bird of a Feather (1 hour)
2025 : full dev room (half a day). Videos, slides and schedules