After a PhD in Computer Science, I went back to medical school to get a M.D. Now, I specialize in molecular genetics. I also contribute frequently to open-source projects, especially for Nix packages in bioinformatics.
Research
Publications:
- Dellal, Hadjer, Roman Klifa, Lise Larcher, et al. 2026. “From a Novel Pathogenic SAMD9L Variant to Cohort‐wide Insights: Whole‐genome Sequencing Highlights Somatic Genetic Rescue and Phenotypic Heterogeneity.” British Journal of Haematology, ahead of print, May.
- Labalette, Vincent, Alexis Praga, Florent Girard, Martine Meireles, Yannick Hallez, and Jeffrey F. Morris. 2021. “Shear-Induced Glass-to-Crystal Transition in Anisotropic Clay-Like Suspensions.” Soft Matter 17 (11): 3174–90.
- Praga, A., D. Cariolle, and L. Giraud. 2015. “Pangolin V1.0, a Conservative 2-d Advection Model Towards Large-Scale Parallel Calculation.” Geoscientific Model Development 8 (2): 205–20.
- [Praga, A., T. Z. Hirsch, D. Vidaud, et al. 2025. “Hepatoblastoma in a Patient with Neurofibromatosis Type 1: A Case Report.” Cancer Genetics](292-293 (April): 35–37. https://doi.org/10.1016/j.cancergen.2025.01.005.)
- Dellal H, Klifa R, Larcher L, Passet M, Celse T, Gouas L, Tusseau M; AURAGEN Consortium; Praga A, Bernard V, Fusaro M. From a novel pathogenic SAMD9L variant to cohort-wide insights: Whole-genome sequencing highlights somatic genetic rescue and phenotypic heterogeneity. Br J Haematol. 2026 May 19. doi: 10.1111/bjh.70563. Epub ahead of print. PMID: 42154215.
Talks:
- Assises de Génétique (2026): BARACUDA : Un outil de priorisation et visualisation des aneuploïdies et des disomies uniparentales en mosaïque dans les maladies rares
- ACLF (2025) : BARACUDA : Un outil de priorisation et visualisation des CNV en mosaïques et des disomies uniparentales dans les maladies rares
- FOSDEM (2024) : Nix for genetics : powering a bioinformatics pipeline (lighthing talk) - slides, official website
- JCADD (2024) : Un pipeline reproductible pour la réanalyse de données d’exome en génétique - slides, talk, source code (Software Heritage)
Others:
- PhD manuscript: A large-scale atmospheric chemistry-transport model for massively parallel architectures
- Medical thesis: Un pipeline bioinformatique de ré-interprétation d’analyses constitutionnelles d’exome
Open-Source
With my fellow co-organizers, we added Bioinformatics at FOSDEM:
- 2024: my talk about Nix (see above)
- 2025 : Bird of a Feather (1 hour)
- 2025 : full dev room (half a day). Videos, slides and schedules